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Methandrostenolone (Dianabol)

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by Bill Roberts - Contrary to what many would expect, Methandrostenolone compound is actually only a weak agonist of the androgen receptor (AR), with poor binding. It follows, then, that its value must mostly come from non-AR-mediated effects. It is therefore a Class II steroid. Since it is not very effective in activating ARs, it should be stacked with a Class I steroid that is effective in this regard, such as Primobolan, Deca Durabolin, or trenbolone acetate. There is no point in stacking it with Anadrol®, which has similar activity -- one ought to simply use the more appropriate drug. With testosterone or Deca, Dianabol is to be preferred; with Primobolan or trenbolone acetate, Anadrol® is to be preferred (though Dianabol is still a good choice) because Anadrol® does not aromatize. For an oral-only cycle -- something I don't recommend -- Anadrol® is the better choice in my opinion for that also, at 150 mg/day (preferably divided to 3 or 6 doses.)

Methandrostenolone converts to estradiol via aromatase. The amount of this conversion may be reduced by use of Arimidex, or less preferably Cytadren (see previous articles discussing dosage and dose pattern.) Or if the conversion is allowed, Clomid may be used to block adverse estrogenic effects.

Irreversible hoarsening of the voice has been seen in some women from very few tablets of Dianabol: one per day for a few weeks. For this reason, in the 1960s doctors decided to end what had been a fairly common practice of prescribing this drug at one tab per day to women as a "tonic." It is not a good choice for the woman who chooses to use anabolic steroids.

The usual dosing for men is 25-50 mg/day in divided doses, preferably four or five doses. The drug is 17-alkylated and so use should be limited to no more than 6 weeks, and preferably no more than four weeks, with at least an equal amount of time off.

Methandrostenolone is the chemical name of active ingredient in Dianabol. Dianabol was originally a registered trademark of Ciba-Geigy Corporation in the United States and/or other countries prior to cancellation.

Dianabol Resources

Dianabol Pictures
Dianabol Steroid Profile from Anabolics 2007

Dianabol Pictures and Photographs

Dianabol Chemical Structure

Substance name Metandienone [INN]; Methandrostenolone; Methandienone
Chemical name

17ß-hydroxy-17a-methylandrosta-1,4-dien-3-one

Systematic name (8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13,17-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
Index name Androsta-1,4-dien-3-one, 17-hydroxy-17-methyl-, (17beta)-
CAS registry number 72-63-9
Merck Index Number Merck 11, 5862
Molecular formula C20-H28-O2
Molecular weight 300.435 g/mol
Legal status Illegal (US); DEA Schedule III (US)
Routes of administration Oral

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