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by Anthony Roberts - Trenbolone Enanthate
is a strictly underground product, and not available
for human use by any major pharmaceutical supply
house in the world. It combines a very popular parent
hormone (trenbolone) with a long acting ester (enanthate).
This allows the advantage of once a week injections.
Background
For a fairly long time, the only version of legitimate
Trenbolone available on the black market was
Trenbolone Acetate.
This was a fast acting version of Trenbolone often
made from powder or cattle implant pellets. Since
Parabolan (Trenbolone
with a slightly longer ester) had been removed from
the market, it developed a cult-like reputation,
and a longer acting Trenbolone product was in demand
on the black market. The underground labs of the
time responded with Trenbolone Enanthate.
Steroid Action
Trenbolone is a19-nor steroid, very similar to
Nandrolone. The
primary difference between Trenbolone is that there
is a double carbon bond present at the 9 and 11
position on the steran nucleus. Trenbolone can not
aromatize to estrogen nor be 5a-reduced.
It bonds very tightly to the Androgen Receptor,
and for this reason it is thought that much of its
fat-burning and muscle building abilities are receptor
mediated.
Technical Data
Trenbolone use produces an impressive amount
of new muscle fiber, with minimal water retention
(1) This may be done partly through an increase
in IGF-1 within muscle tissue (2), and increased
sensitivity of muscle satellite to IGF-1 and other
growth factors(3) and an increase in the amount
of DNA per muscle cell.
It has a very strong binding affinity to the
androgen receptor (A.R), binding much more strongly
than testosterone (4) as well as nandrolone.
Trenbolone increases both protein synthesis as
well as nitrogen retention in muscle tissue (5).
Trenbolone can also bind with the (anti-anabolic)
glucocorticoid receptor (6-7), thus aiding the muscle
building process.
Finally, it also has the ability to improve nutrient
efficiency and mineral absorption in animals given
the drug (8-9).
User Notes
You have probably noticed that there is no “Technical
Data” for Trenbolone Enanthate per se (all of the
studies cited are actually on Trenbolone with a
different ester)
Well…there’s a very good reason for that. As
noted previously, this is a strictly underground
product…so while you will easily be able to find
it available from GA Labs or DL Pharmaceuticals
INC., you will not find it available from UpJohn
or Steris. In fact, at this point, you will only
find Trenbolone (Acetate) available in the veterinary
industry.
In my experience with Trenbolone Enanthate, it
is a very potent cutting agent, and will even help
keep you lean while on a bulking cycle (it did for
me, anyway). However, it will also cause some undesirable
effects as well. It can cause insomnia and night
sweats, as well as possible anxiety. It seems to
not cause “tren cough” (coughing associated with
Trenbolone Acetate) but still seems to reduce cardiovascular
ability.
All in all, though, Trenbolone (any ester) is
a really great drug for both building muscle as
well as burning fat. It’s probably most people’s
favorite behind testosterone, side effects be damned…and
for good reason.
If you’re not a competitive athlete, this is
a really great drug. Bodybuilders love the stuff,
and we see it in many pre-contest cycles now-a-days.
Athletes need to avoid it, however, because it simply
reduces cardiovascular output too greatly, probably
due to prostaglandin induced bronchial constriction.
Trenbolone Resources
Trenbolone Pictures
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| Substance name |
Trenbolone [INN] (base) |
| Chemical name |
17ß-hydroxestra-4,9,11-trien-3-one
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| Systematic name |
(8S,13R,14S,17S)-17-hydroxy-13-methyl-2,6,7,8,14,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-3-one
|
| Index name |
Estra-4,9,11-trien-3-one, 17-hydroxy-,
(17beta)- |
| CAS number |
10161-33-8 |
| Merck Index Number |
Merck 11, 9499 |
| Molecular formula |
C18-H22-O2 |
| Molecular weight |
270.366 g/mol |
| Legal status |
Veterinarian
Use Only (US); DEA Schedule III (US) |
| Routes of administration |
Intramuscular |
| Year introduced |
1979 |
References
- Br J Nutr. 1978 Nov;40(3):563-72.
- J Cell Physiol. 2004 Nov;201(2):181-9.
- Endocrinology. 1989 May;124(5):2110-7.
- Toxicol Sci. 2002 Dec;70(2):202-11.15
- J Anim Sci. 1994 Feb;72(2):515-22.
- APMIS. 2001 Jan;109(1):1-8.
- J Anim Sci. 1990 Sep;68(9):2682-9.
- APMIS. 2001 Jan;109(1):1-8.
- J Anim Sci. 1992 Nov;70(11):3381-90.
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